Is it ok if i take sam-e and 5-htp together?

Probably safe but...: There's no research on this but it's probably safe to take these together, in fact I'd expect a synergistic benefit. SAMe appears to increase serotonin levels; 5-HTP does that too so theoretically one might raise serotonin too much, but this is unlikely unless very high doses are taken. I would not start both together but take one for at least 3 weeks, then add the other, starting with low doses.