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Pittsburgh, Pennsylvania
A 37-year-old female asked:

I take methotrexate (15mg) once a week for arthritis. i have to take a 1 dose of diflucan for a yeast infection, do i need to stop the methotrexate?

2 doctor answers2 doctors weighed in
Dr. Hunter Handsfield
Infectious Disease 53 years experience
No problem: There is no interference between methotrexate and fluconazole (Diflucan®).
Dr. Samantha Maplethorpe
Family Medicine 22 years experience
Methotrexate: This is a really important question for your Rheumatologist, they will know your history best and should be able to give the best advice.

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Last updated Feb 3, 2017

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