Can oxycodone 5/325 be taken on an empty stomach?

Yes: Yes, but it will be easier on your stomach if you have light snack and fluids before taking medicine.

Medication: Yes, oxycodone may be taken without food. Some patients report nausea without food ( yoghurt, milk, crackers).

Yes but: Be very careful with this mediciation. If you become dependent on it, the loss of it can make you very sick and change your body's response to pain.