A member asked:

When should i increase dose on metformin i'm taking 500mg with no side effects. have to get to 1500mgs don't want to get the horrible side effects?

3 doctors weighed in across 2 answers

Check w/doctor: Metformin must be 2x/day to be effective. Most effective dose is 2000/d. Increase in 500 mg steps each week to avoid side effects.

Answered 2/6/2019

5.2k views

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Dr. Quang Nguyen answered

Specializes in Endocrinology

Gradual: If you have no problem with the 500 mg, try taking a pill with dinner and if ok in 1 week, increase it by 500 mg more. It should be taken twice per day.

Answered 2/6/2019

5.2k views

Thank

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