U.S. doctors online nowAsk doctors free
Tewksbury, MA
A 55-year-old female asked:

My fiance just had his routine checkup and his blood work came back normal except for he has a lot of enlarged red blood cells?

2 doctor answers3 doctors weighed in
Dr. Charles Rocamboli
Family Medicine 19 years experience
Vitamins: He may be deficient in Folic Acid or vitamin b12. This sometimes happens with certain parasites (like tapeworms) or diseases (like pernicious anemia). However, in the United States is much more commonly associated with alcoholism.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Alvin Lin
Geriatrics 31 years experience
Macrocytosis: Macrocytosis (mcv >100) is commonly due to vitamin B12 +/- folate (folic acid) deficiency. That's next step in evaluation. Luckily, both vitamins are inexpensive & available in large enough doses as a pill (even w/severe gastritis). Shots aren't considered necessary to treat low B12 anymore as 1, 000mcg daily can overcome lack of intrinsic factor. Btw, macrocytosis often associated w/excess alcohol, low thyroid.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Alvin Lin
Dr. Alvin Lin commented
Geriatrics 31 years experience
Provided original answer
Apr 14, 2013
Last updated Jun 25, 2014

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.