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Tewksbury, MA
A 55-year-old female asked:

My fiance just had his routine checkup and his blood work came back normal except for he has a lot of enlarged red blood cells?

2 doctor answers3 doctors weighed in
Dr. Charles Rocamboli
Family Medicine 18 years experience
Vitamins: He may be deficient in Folic Acid or vitamin b12. This sometimes happens with certain parasites (like tapeworms) or diseases (like pernicious anemia). However, in the United States is much more commonly associated with alcoholism.
Dr. Alvin Lin
Geriatrics 30 years experience
Macrocytosis: Macrocytosis (mcv >100) is commonly due to vitamin B12 +/- folate (folic acid) deficiency. That's next step in evaluation. Luckily, both vitamins are inexpensive & available in large enough doses as a pill (even w/severe gastritis). Shots aren't considered necessary to treat low B12 anymore as 1, 000mcg daily can overcome lack of intrinsic factor. Btw, macrocytosis often associated w/excess alcohol, low thyroid.
Dr. Alvin Lin
Dr. Alvin Lin commented
Geriatrics 30 years experience
Provided original answer
Apr 14, 2013

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Last updated Jun 25, 2014

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