Multiple causes: Tendon inflammation and rupture from Levaquin (levofloxacin) and related antibiotics appears due to multiple factors including inhibition of fibroblast proliferation, decrease in collagen and proteoglycan synthesis, magnesium depletion, toxicity to mitochondria and DNA damage. See http://www.medscape.com/viewarticle/464865_2 and http://www.tendonitisexpert.com/levaquin-tendonitis.html for details.
Answered 1/5/2019
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