Can you be on dexilant (dexlansoprazole) for long term, like over a year? if so do you have to watch anything?

Dexilant (dexlansoprazole) long term: Dexilant (dexlansoprazole) - the active isomer of Prevacid is approved for treatment up to 8 weeks. Long term use - over a year has been associated with bone fractures and osteoporosis. Electrolyte abnormalities (low magnesium) have also been reported. I would caution long term use and if needed take the lowest dose and consider having a GI evaluation if symptoms persist.