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Grandview, TX
A 56-year-old female asked:

how long does one orlistat pill last?

2 doctor answers2 doctors weighed in
Dr. Matthew Nelsen
Internal Medicine 25 years experience
1-2 Hours: The half life is 1-2 hours. That means that the medicine only stays in your intestines for a few hours. In 2 hours, only 60mg is still effective if you took a 120mg pill. That is why it must be taken with food.
Dr. Matthew Nelsen
Internal Medicine 25 years experience
Provided original answer
Agree with Dr. Lin that it will take 5-10 hours to be completely out of your system. There is a lot of variability in transit through GI.
Apr 8, 2013
Dr. Alvin Lin
Dr. Alvin Lin answered
Geriatrics 30 years experience
Half-life = 1-2hrs: https://online.epocrates.com/noframe/showpage.do?method=drugs&monographid=2062&activesectionid=7 lists half-life of orlistat (sold as xenical & alli) as 1-2hrs. Most drugs are theoretically out of your system after 5 half-lives. In this case, you're looking at 5-10hrs.

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A 34-year-old member asked:

Is it okay to take co codamal and orlistat together?

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Yes: Yes, it's okay to take together.
A 40-year-old member asked:

What will happen if you don't eat but still take your orlistat pills?

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No: Not necessary, if it not eating you dont.
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How quickly does orlistat begin to work?

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45 minutes: Usually within a few minutes.
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Is it ok to mix orlistat and fat burners?

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A 27-year-old member asked:

What happens if you are taking orlistat pills and you skip a meal but you don't skip your pill?

4 doctor answers5 doctors weighed in
Dr. Ray Holt
Dr. Ray Holt answered
Family Medicine 28 years experience
Nothing: You'll just be wasting a pill, because it has no meal to work on.

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Last updated Sep 14, 2016

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