A female asked:
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what makes you gain weight on anti depressants? do they affect metabolism? i gained on cymbalta (duloxetine) and hardly ate-no appetite, still worked out? why?

1 doctor answer
Dr. John Moranville
35 years experience Psychiatry
Unclear: unfortunately weight gain is a common side effect of most antidepressants and the mechanism is unclear, but I often hear stories similar to yours. Cymbalta (duloxetine) is supposed to be weight neutral but in my experience venlafaxine (Effexor) and bupropion (Wellbutrin) are least likely to cause weight gain
Answered on Jun 18, 2019
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