No: This means nothing. Reference ranges are set so that a few percent of healthies are over the top. This is just a little extra carrier protein shuttling the vitamin around.
Answered 10/15/2017
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Very high level: The abnormal lab value needs to be further addressed. Can be caused by increase in the blood protein that carries B12 (made by blood cells), or liver or kidney problems. If basic labs for liver/kidney are normal, the next step is to screen for problems related to the bone marrow and blood cell production or for inflammatory disorders. Vitiligo (autoimmune attack of pigmented cells) could explain.
Answered 3/31/2016
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