Is there interaction between xanax (alprazolam) and macropen. taking xanax (alprazolam) 3 times a day 0.25 mg, now affraid it can do me harm?

No bad reports: It should be safe, but ALWAYS discuss this sort of thing w/ the Dr prescribing! Always! Also consider CBT therapy to learn how to manage so much anxiety w/ less drugs. 3X/day says you can probably do better w/ learning. I hope you feel better soon - try not to worry but do take the opportunity to talk about your anxiety in non-drug ways.