A 49-year-old male asked:
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fatigue 1 year, muscle loss but central weight gain, low sodium (135), cortisol at top of range, could this be an early stage sclc. ct was negative.

1 doctor answer
Dr. Jesse Krakauer
44 years experience Endocrinology
Yes - but very rare: B"sd do you mean small cell lung cancer? Elevated cortisol can be related to stress or to pituitary, adrenal or rarely, ectopic ACTH as in lung cancer. The best screening test is late night salivary cortisol (or a blood cortisol - but this is inconvenient in late PM). Normal cortisol is highest in the AM and close to zero late in the day. This is complicated. Glad to discuss.
Answered on Mar 16, 2016
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