Oncologist--radiation and chemo does very little for pancreatic cancer due to desmoplasia. is there a way to deal with this fibrotic issue? thanks.

You are partly right: Yes, Pancreatic cancers tend to create Desmoplasia....that is the explanation given for the limited benefit from chemotherapy. Yet there are now 3-4 drugs which have good penetration into the tumor and have produced moderate degree of beenfit for some pateints. i would advise you to ask your oncologist to treat you with the current best chemotherapy drugs of which there are 2 well known regimens.