A member asked:

Diagnosed with sciatica yesterday. on percocet, flexeril, (cyclobenzaprine hcl) toradol, and prednisone. why does the percocet make me "speedy" even when i take one 5mg?

7 doctors weighed in across 2 answers
Dr. Krishna Kumar answered

Specializes in Psychiatry

I understand your distress. You are taking 2 antiinflammatory medications-Toradol and Prednisone. Percocet is narcotic for pain, it may cause restlessness and agitation. See Orthopedic Physician , have MRI to find exact source of symptoms, bulging or herniated disc; discuss need for specific medications, dose and side effects, need for Percocet or other pain medications, PT ; follow up

Answered Jun 18, 2022


Dr. Brian Clear answered

Specializes in Family Medicine

As an opiate pain medication, Percocet causes dopamine release in addition to blocking pain signals, and the dopamine causes a sensation of euphoria. The most effective treatments for sciatica are gently progressive stretching exercises and anti-inflammatory medication. Naproxen is preferred over Toradol. The other 3 are helpful in some situations but dubiously beneficial in the long term.

Answered Dec 26, 2015



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