Cytokines: Most systemic symptoms of infection -- fever, achiness, loss of appetite, sleepiness, and others -- are the result of chemicals called cytokines, which are released by white blood cells as they fight infection. Almost any infection can do it, not only influenza. Particular symptoms (achiness, fever, etc) are vary widely between individuals and from one kind of infection to another.
Answered 12/19/2015
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