No sleep for 5 days now, i forget to eat a lot of the time & my anxiety/depression is bad lately. can these affect my adhd meds effectiveness?

Or vice-versa. What : you & your psychiatrist need to sort out is whether your symptoms are the first indication of a mood disorder, as can happen in late adolescence -early adulthood &/or if your stimulants are triggering the onset of these symptoms & what to do about them. Are you on Adderall or Vyvanse (lisdexamfetamine)? Don't drive when sleep-deprived that long. Do have someone drive you to an appointment with your psychiatrist.

INSOMNIA: Good night's sleep is important for physical & mental health. Insomnia might be due to several reasons. Have a physical exam to rule out illness. If cleared consult with a Clinical Psychologist with expertise in multiple types of psychotherapy that helps you benefit from medication prescribed by a Psychiatrist & possibly a sleep study.