Can i crush/break upmalaria tablets (atovaquone(250mg)/proguanilhydrochloride(100mg), film-coated, i can't swallow these they are too big?

Malarone's crushable: Yes- according to the GSK package insert (the makers of the malaria tab atovaquone/proguanil) you can crush the tabs for easier swallowing. They studied it so you can do the same. See pg 20 of the package insert if you really want the details! Make sure to take these meds! https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Malarone/pdf/MALARONE.PDF