A member asked:

My dad died suddenly on mar 7th after having chest pain and numb legs, it was probably sudden cardiac death. he had a little heart attack 4 y ago and took seroquel, (quetiapine) can that be the reason?

12 doctors weighed in across 7 answers
Dr. Bahman Omrani answered

Specializes in Pain Management

Common....: Things are common. Basing the answer purely on epidemiological data, the death was most likley due to a heart attack. Depending on the exact type of heart disease, certain medications, including seroquel (quetiapine) can interfere with the hearts electrical activity and lead to sudden cardiac death.

Answered 12/9/2013

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Dr. Stevan Cordas answered

Specializes in Internal Medicine

Chest pain.: Or an aneurysm. Probably was the heart.

Answered 4/7/2013

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Dr. Thomas Namey answered

Specializes in Rheumatology

Not likely!: Athersclerosis takes years to develop. Obviously there were risk factors that had not been dealt with. Seroquel (quetiapine) can cause weight gain, but the fact he previously had a heart attack, suggest that his arteries were obstructed four years ago. Sorry for your loss!

Answered 12/10/2013

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See below.: Sudden cardiac death is one of the most common causes of death esp in people who have known heart disease. Seroquel (quetiapine) would have nothing to do with this.

Answered 4/7/2013

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Dr. Tonga Nfor answered

Specializes in Cardiology

Sudden death: I am so sorry for your terrible loss! seroquel (quetiapine) can increase risk of sudden death from abnormal heart rythms when taken at a high dose and in combination with other medications that affect electrical conduction in the heart. From the information you give another heart attack is the most likely cause of death.

Answered 5/6/2013

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Cant tell but --: Seroquel (quetiapine) can cause metabolic changes that can increase your lipids and increase risk of diabetes which in turn can effect other systems like heart and brain. So, if your father took seroquel (quetiapine) 4 yrs ago and has been taking it all this time then it may have contributed. Why was he put on seroquel (quetiapine) ? Elderly people should be placed on seroquel (quetiapine) very carefully.

Answered 10/24/2017

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Dr. Theresa-Ann Clark answered

Specializes in Family Medicine

Heart history likely: So sorry you lost your dad. A history of heart attack and numb legs means probable coronary and peripheral artery disease, often known as "clogged arteries". Blockages (caused by cholesterol) in arteries interrupt blood flow cutting off oxygen to heart muscles that die. Seroquel (quetiapine) can increase cholesterol levels. Treatment is a balance of risks: using medication vs. Not treating diseases.

Answered 9/28/2016

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