I take 50 mg seroquel (quetiapine) and 25 mg escitaloprom, what is my risk of heart problems? is this a total contraindication? should i do ecg? blood test?

See below: Escitalopram and Seroquel (quetiapine) can each increase QTc interval. When combined the risk of QTc prolongation increases further. The combination is not a total contraindication unless you have a history of one of the following: bradycardia, CHF,congenital QT prolongation, hypokalemia, low magnesium, family history of long QT--blackouts or sudden death. If non of the above an ECG isn't mandatory.*Comments

Yes.: Escitalopram at 25mg is a high dose. High doses of serotonin retake inhibitors combined with non-steroidal anti-inflammatory meds like asprin, Motrin can lead to stroke. If you notice easy bruising let your doc know. Furthermore seroquel (quetiapine) can cause prolongation of the qt syndrome in the heart for people who are prone to it. Generally the combo is safe but I would get an ekg to be safe.

Low immediate risk: Ur Seroquel & Lexapro dose r both on the low side, so I doubt u'll experience any problems short-term. There r rare case reports of QT prolongation, a type of EKG abnormality, from Seroquel, but w/ higher doses. Many pts take Seroquel & Lexapro together w/o problems. However, long-term, Seroquel can cause diabetes & metabolic risk 4 heart disease. So, consider alternatives like Geodon (ziprasidone) in abt 1 yr.