My father accidently had taken300mg of seroquel (quetiapine) and100mg of tramadol. he has heart problems, tripple by pass, and high blood pressure, what should i do?

Call your doctor: Would call your doctor .He may recommend going to the er to be checked out.

Call poison control: Your father should contact your local poison control hotline or call national poison control at 1-800-222-1222. He may need to go see his doctor or the er depending on how toxic the dose is for him. Poison control has extensive information about drugs and chemicals with advice on how to proceed safely. The same dose can affect different people differently.

Is he awake?: Is your father awake? And what doses of these medicines has he been prescribed? These amounts could be in a normal range, although more than he's used to taking. If he's awake and feeling fine, he may have no sequelae. Please call your father's own physician and ask advice -- s/he knows your dad & how these meds typically affect him. Take him to an er if anything at all seems amiss.