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A 48-year-old female asked:

can your mri of the spine be negative for ms, but your brain mri postive?

2 doctor answers5 doctors weighed in
Dr. Dariush Saghafi
Neurology 33 years experience
MY MRI's?: Well, thanks for asking. MY MRI's of the spine and brain...well, they're very well thank you..;) But I guess we're talking about maybe YOUR MRI's? I need to say 1 very important thing. Listen up...MRI's don't diagnose MS..qualified people do. An MRI of a spinal CORD can definitely NOT show signs CONSISTENT with MS while a brain's does. Make sense? Maybe? Got pictures? ww.healthtap.com/drsaghafi
Dr. Anne Phelan-adams
A Verified Doctor commented
A US doctor answered Learn more
MS causes plaques in the central nervous system which includes both the brain and the spinal cord. These plaques are areas that lack myelin, a protein that helps conduct nerve signals to the rest of the body. Plaques can be present in the brain or spinal cord or both but presence or absence of plaques alone doesn't confirm or rule out MS.
Oct 13, 2015
Dr. Edward Hellman
Orthopedic Surgery 29 years experience
Yes: Yes one of the findings often seen in ms is characteristic " plaques" seen on MRI scans. These can be in the brain and not anywhere else potentially. The presence of plaques does not in and of itself make the diagnosis, so you would want to see a neurologist for accurate workup, diagnosis, and treatment.

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