How to make yourself feel better when sick?

Rest: and fluids are rather important for most any illness. Specific remedies would be different for different illnesses.

Depends . . .: How sick is sick? What kind of sickness? Only time will help you get better from common cold - antibiotics won't make a difference. But you'll need (appropriate) antibiotics to treat bacterial infections like some sexually transmitted or urinary tract infections. Drinking enough fluids might help deal w/dehydration from hangover. Go see FamilyDoc if sickness persists despite over-the-counter meds.