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Secaucus, NJ
A 34-year-old male asked:

Losartan alternative for kidney patient (creatinine 2.7) that will not result in hyperkalemia?

2 doctor answers4 doctors weighed in
Dr. Ronald Hamner
Nephrology and Dialysis 43 years experience
No: Any medicine that inhibits the Renin-Angiotensin System (RAS) can reduce kidney handling of potassium. Losartan stops angiotensin effect in the kidney and may have less effect on potassium but remains a cause of hyperkalemia. Drugs that are "ACE inhibitors" or "ARB" agents can increase potassium. They can be used if a low potassium diet is followed and potassium levels are followed closely.
Dr. Jack Rubin
Nephrology and Dialysis 48 years experience
Losartan alternative: Losartan (L) is an ARB and is one of the drugs that affect the renin-angiotensin-aldosterone system (RAAS). All drugs that affect it, such as ARB's and ACE-Inhibitors can raise potassium (K). These drugs not only lower BP they also lower protein in the urine, which is a good thing. If your K becomes elevated, ask your physician about drugs that can lower it, such as lasix, (furosemide) so you can take L..

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Last updated Oct 7, 2015

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