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Secaucus, NJ
A 34-year-old male asked:

Losartan alternative for kidney patient (creatinine 2.7) that will not result in hyperkalemia?

2 doctor answers4 doctors weighed in
Dr. Ronald Hamner
Nephrology and Dialysis 45 years experience
No: Any medicine that inhibits the Renin-Angiotensin System (RAS) can reduce kidney handling of potassium. Losartan stops angiotensin effect in the kidney and may have less effect on potassium but remains a cause of hyperkalemia. Drugs that are "ACE inhibitors" or "ARB" agents can increase potassium. They can be used if a low potassium diet is followed and potassium levels are followed closely.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Jack Rubin
Nephrology and Dialysis 50 years experience
Losartan alternative: Losartan (L) is an ARB and is one of the drugs that affect the renin-angiotensin-aldosterone system (RAAS). All drugs that affect it, such as ARB's and ACE-Inhibitors can raise potassium (K). These drugs not only lower BP they also lower protein in the urine, which is a good thing. If your K becomes elevated, ask your physician about drugs that can lower it, such as lasix, (furosemide) so you can take L..
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Oct 7, 2015


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