Is luvox and wellbutrin (bupropion) a safe combo in treating ocd, anxiety and depression?

Alternative: These meds. have the possibility of interacting with each other (although this can be minimized by starting with a low dose). That said, there are safer alternatives. Personally, I tend to try Pristiq (desvenlafaxine) + Wellbutrin XL for patients who aren't doing well on an SSRI alone. But this is a matter of prescriber preference and what your physician feels is the most appropriate for you. Hope that helps!