What causes duodenal ulcer?

Most commonly: Related to acid insult and treated with proton pump inhibitors or h2 blockers.

H. pylori: The majority of ulcers are caused by this bacterium helicobacter pylori. Other causes may involve high doses of anti inflammatory drugs or rarely tumors that secrete gastrin causing acid hyper secretion- zollinger ellison syndrome.

Acid, bacteria: Duodenal ulcers are assoc with a bacteria (h.Pylori) in the majority of cases. Other causes include: too much acid production, which can be seen with certain conditions/medications:(cushings/cortisol, stress, some tumors, short bowel length), toxins(alcohol, nsiad's-iboprofen).

Duodenal Ulcers: The most common cause of duodenal ulcer is a stomach infection associated with the helicobacter pylori (h pylori) bacteria. Other risk factors for duodenal ulcers include overuse of alcohol, tobacco, and medications such as Aspirin and nonsteroidal anti-inflammatory drugs (nsaids). Severe illness has also been implicated as a risk factor in the development of duodenal ulcer.