I have a row of very painful itchy blisters under my right breast.i also have a burning itching in my rectum area.do you think these 2 issues related?

Hard to know: without seeing you, Maryamj, but it sounds like you might have a fungal infection which can occur in any tight space where there is trapped sweat and is called intertrigo. These infections are especially common in diabetics, so you should be checked for that, especially if you have a family history or are overweight. Meanwhile, try Cruex powder and keep the areas very dry, perhaps with tissue.