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A member asked:

Is there a reliable molecular test for assessing remission status of mantle cell lymphoma?

A doctor has provided 1 answer
Dr. Matthew Fero answered

Specializes in Medical Oncology

Mantle Cell Lymphoma: ...is a type of non Hodgkin's lymphoma characterized by the genetic rearrangement of two chromosomes. This causes an abnormal fusion of two genes: Immunoglobulin (IgH) and Cyclin D1. Molecular studies that can detect this abnormality includes either FISH or RT-PCR. Flow cytometry is also good at identifying abnormal cells based on cell surface antigen expression.

Dr Feola agreed

Answered 1/3/2016

2.4k views

Thank

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