A member asked:

Is it safe to take benadryl (diphenhydramine) with vicodin?

A doctor has provided 1 answer
Dr. Paul Grin answered

Specializes in Pain Management

It is safe: However, taking benadryl (diphenhydramine) with Vicodin could increase the chances of central nervous system and respiratory depression. Always ask your physician for advice in weighing the dangers against the benefits.

Answered 7/30/2018

2.5k views

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