HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

5/325 norco (hydrocodone and acetaminophen) and 25 mg diphenhydramine at the same time for itching ok?

A doctor has provided 1 answer
Dr. Robert Grindstaff answered

Specializes in Addiction Medicine

Probably: the combination may cause increased CNS depression but at these doses it should be ok

Dr Cunningham and 2 doctors agreed

Answered 8/4/2019

3.7k views

Thank

Related Questions

A member asked:

Can I take a viccon an a norco (hydrocodone and acetaminophen) at the same time?

5 doctors weighed in across 3 answers

A member asked:

If you stop taking norcos, (hydrocodone and acetaminophen) can a drop show up negative five days later? Herniated l5

A doctor has provided 1 answer

A member asked:

Can you take Cephalexin 500mg, Norco (hydrocodone and acetaminophen) 10-325, and pantoprazole 40mg at the same time?

2 doctors weighed in across 2 answers

A member asked:

Will norco (hydrocodone and acetaminophen) show up in a drug test 10/325 3 times a day last time i took it was 9:00pm will it show in a drug test the next morning at 9:00am?

4 doctors weighed in across 2 answers

A member asked:

Can you take norco (hydrocodone and acetaminophen) and flexeril at the same time?

4 doctors weighed in across 2 answers

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

If i'm allergic to norco (hydrocodone and acetaminophen) should I continue to use them? They make me itch all over even 5 hours after taking, but its bearable. Should i stop taking them?
Is norco (hydrocodone and acetaminophen) Vicodin? I saw a new doctor and they gave me pain meds and forgot to tell them I can't take Vicodin as it makes me itch.
What is the time release regarding Norco (hydrocodone and acetaminophen) 10/325 vs Opana 40 mg?
So ur saying it's ok to take tramadol and norco (hydrocodone and acetaminophen) at the same time?
Norco (hydrocodone and acetaminophen) 10/325 vs opana 40 mg time release, what to do?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.