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A 50-year-old male asked:

In case of severe acid reflux is it ok to take nexium (esomeprazole) and zentac same day few hours apart ?

1 doctor answer1 doctor weighed in
Dr. Donald Lipkis
Gastroenterology 49 years experience
Not necessary: Even though it is not dangerous to take these medications 2 hours apart, it is not necessary. You will not achieve any additional benefit. If The Nexium (esomeprazole) is not controlling acid reflux throughout the day you can take a Zantac 12 hrs later or at bedtime.
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Last updated Jul 10, 2015

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