What is the most effective medicine for migraine and the best treatment for migraine?

R/O MIGRAINE : The 4 basic headaches are Tension, Sinus,migraine and cluster. MIGRAINES can have a PRODROME beforehand . Rest /ice and a darkened room may help. Also a NSAID like Aleve (naproxen) /daypro. /Triptans. HI FLOW O2. Meditation/Yoga/Biofeedback. GF DIET WHOLEAPPROACH.com You need a full exam an blood work to be through. If symptoms worsen seek medical evaluation

Older medicines: The ones usually given are the tryptans. They are expensive and also dangerous with regard to serious effects of vasoconstriction. A multi center study of emergency room treatment of migraine revealed the superiority of phenothiazine–antihistamines such as Phenergan (promethazine) and Compazine. 1 antinausea dose tab at onset, repeat in ½ hr if needed. Repeat sequence 2 hrs from 1st dose.

Suggestions: Preventative approaches may work the best in the end. OTC items such as butterbur, feverfew, Co-Q10, riboflavin, and magnesium may work as well or better than drugs. Triptans can stop headaches if used early, but work poorly after 90 min. Never use pain meds such as narcotics, as things can get worse.