A member asked:

Does dot and fleck retinopathy look specific if it's alport?can you have a small amount of mottling on retina and not be alport ?

A doctor has provided 1 answer
Dr. Richard Roberts answered

Specializes in Pediatrics

Yes and no: With a family history of Alport disease and/or renal failure, the dot-and-fleck retinopathy is diagnostic. "A peripheral retinopathy in the mother of a male with hematuria suggests X-linked inheritance, and central retinopathy or lenticonus in a female means that recessive disease is likely. Ocular examination, retinal photography, and optical coherence tomography are widely available" for Dx.

Answered 6/28/2015

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