A member asked:

How long does it usually take for duloxetine (cymbalta) 60mg to leave the brain?

A doctor has provided 1 answer
Dr. James Rochester answered

Specializes in Family Medicine

75 hours roughly: half life of drug is about 15 hours. Need 5 half lives to clear 95% from your system. HOWEVER, this is NOT a medicine you should just stop. It MUST be weaned SLOWLY. If thinking of stopping, please discuss with your doctor. Dr. R

Answered 5/2/2016

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