U.S. doctors online nowAsk doctors free
A 54-year-old female asked:

Why is my sed,crp normal even with pleurisy and swollen joints and prednisone is only thing that helps? sle. why does it not pick up on the inflamm?

1 doctor answer3 doctors weighed in
Dr. Ed Friedlander
Pathology 45 years experience
No easy answer: Please forgive me. Sed rate and C-reactive protein are famously unreliable markers for inflammation in lupus and suspected lupus. A different pathway of inflammation is often involved. Despite "pop" ideas about "inflammation", inflammation enormously complicated. If it weren't, common painkillers would clear depression, which some folks describe as "a form of inflammation."

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership
Last updated Jul 18, 2015


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.