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A 50-year-old male asked:

Why does lexapro (escitalopram) cause more migraines than other ssri's?

2 doctor answers3 doctors weighed in
Dr. Patricia Foster
Psychiatry 45 years experience
Hmm...: Am not aware of any studies that support what you say. Where did you read that information? I've not found that true in my experience either with patients on various SSRI's.
Dr. Belinda Stillman
Psychiatry 19 years experience
Serotonergic: Lexapro or escitalopram has greater strength to exert itself upon the serotonin system, which also places it at greater risk of headache and migraine symptoms. Serotonin is a chemical that is found within our nerves and in the synapses, or spaces between our nerves. Lexapro prevents the nerve endings from taking serotonin from the synapses as quickly as might be happening, which alleviates depre
Last updated May 1, 2016

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