Pt with metastic colon cancer with liver and peritoneal mets . can this cause vomitting and fever ?

Possible: It depends on many factors, but those are both possible. Best to see the oncologist for more specifics details regarding your case. Hope this helps!

Yes: Liver and peritoneal mets are not uncommon when a large colon lesion invadesi the blood stream. Vomiting is a sign of retrograde movement of GI content to stomach and up into esophagus. Inflammatory changes associated with the site of the primary can induce the febrile response. PET/CAT can show extent of spread and also visualize partial intestinal obstruction for which decompression required.