Can hydrocodone affect conception?

Maybe: It could alter your prolactin levels.

Probably can: Hydrocodone is technically a synthetic opiate but OPIATES are known to affect pituitary hormones that control female hormonal secretions responsible for regulating the menstrual cycle and ultimately ovulation. So even though hydrocodone specifically does not have data on it I'd counsel you to avoid it on the chance that it be a bad player on your cycle and reduce ovulation and/or egg quality.