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A member asked:

Can losartan(atii rec. blocker) reduce cortisol and norepinephrine?

A doctor has provided 1 answer
Dr. Gary-Anthony Lawson-Boucher answered

ARB: Losartan is an angiotensin receptor blocker. No, it won't lower your cortisol nor ne.

Dr Grin agreed

Answered 12/11/2013

5.2k views

Thank

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I read that norepinephrine reduces brain blood flow. Does snri do that also?

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What effect would you expect Angiotensin Receptor Blockers to have on the brain RAAS in people with Attention Deficit Disorder? Reduction in norepinephrine and sympathetic down regulation through AT1 blockade would reduce attention span and memory?

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Microvascular disease causing angina. Already taking Amlodipine 5 mg (highest dose I could tolerate) Isosorbide mononitrate , beta blocker, Statin , Plavix, Losartan. Still symptoms. What can I take if I am becoming tolerant to nitrates ???

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