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A 36-year-old female asked:

I tested positive for hsv2, low positive 2.5 igg with no symptoms on elisa, but negative on western blot a year after possible exposure. am i hsv2 - ?

1 doctor answer2 doctors weighed in
Dr. Vahe Yetimyan
General Practice 53 years experience
Yes, you are: hsv2- since the western blot test is negative.
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Atlanta, GA
A 32-year-old female asked:

Does the western blot trump the elisa? Tested positive via ELISA IgG for hsv2,but later tested negative via western blot. No symptoms. Do I have hsv2?

1 doctor answer3 doctors weighed in
Dr. Gurmukh Singh
Pathology 51 years experience
Western blot more: specific, ELISA more sensitive. One positive ELISA and one negative Western blot says that you do not have enough antibodies to HSV 2 for confirmation of diagnosis. It may be prudent to repeat the tests in 3-4 months to make sure that negative Western blot was not due to incomplete/early immune response.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated May 3, 2015


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