A 28-year-old female asked:
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tested positive on igg elisa for hsv2. then tested negative on western blot 2 years after last encounter. which test to believe ?

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Dr. Carrie Cannon
A Verified Doctor answered
A US doctor answered Learn more
Western blot: The ELISA screening test is sensitive with a smaller number of false negatives which makes a good screening test. That way fewer true positives are missed. The Western Blot is more specific meaning a smaller number of false positives. A specific test misses few true negatives. It is done for confirmation. You can always repeat the tests in case of specimen mix-up (which I have seen happen before.
Answered on Oct 12, 2014
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Yes, you are: hsv2- since the western blot test is negative.
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Herpes: You have herpes bit already had it prior to this encounter.

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