A 29-year-old female asked:
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tested positive on the elisa test for hsv2, a month later tested negative via western blot 2 years after possible exposure . which test to believe?

1 doctor answer
Dr. Dan Fisher
26 years experience Internal Medicine
Both!: ELISA is very sensitive and sometimes gives a false positive. Interfering substances in serum can make the test look positive. On the other hand, Western Blot is very specific. It does not light up unless you really have antibodies to HSV. So, both tests were "right" , but the Western blot indicates that you do not have the antibody to HSV and have not been exposed.
Answered on Feb 20, 2016
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