A 40-year-old male asked:
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i had a inguinal hernia operation yesterday and was prescribed percocet for pain. i'm also taking zoloft (sertraline). are these safe to take together?

2 doctor answers
Dr. Daniel Bates
8 years experience Family Medicine
Yes: There is a potential interaction between the two medications, causing a rare but dangerous condition called serotonin syndrome. There is only one documented case of this in the literature, and the interaction is more conjecture than fact. In practice I have patients who take both regularly and I have never had an incidence of adverse reactions, so it is probably safe.
Answered on May 3, 2015
Dr. Vahe Yetimyan
51 years experience General Practice
I do not see any: problem taking both together. Usually pharmacy checks drug interections automatically before it is dispensed.
Answered on May 3, 2015

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Dr. Herman Hammerstead
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Yes: Opiate induced constipation Take miralax (polyethylene glycol) and DSS both OTC drugs / daily
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