Depends: .. on the severity of gastric irritation and relative contribution of stomach acidity to the problem. If the pain has not improved in 2 weeks time, then it is likely you are doing something to worsen the irritation (eg taking Nsaid or eating spicy food) or there is another problem that needs to be addressed (eg H pylori infection). Usually you'll need a scope if Nexium (esomeprazole) not working.
Answered 4/24/2015
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