A member asked:

How long will zoloft (sertraline) take to kick in? its 4th day and i still am feeling anxious.

A doctor has provided 1 answer
Dr. Heidi Fowler answered

Specializes in Psychiatry

Zoloft (sertraline): Would expect increase in serotonin levels by around 4 to 6 weeks. However, it will need to be determined if the dose you are on is optimum at that time. Take care & be patient.

Answered 4/26/2015

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