No guarantee: Often the effects of a selective serotonin reuptake inhibitor (like Zoloft (sertraline)) become more prominent after 4 to 6 weeks time. Some people need off label doses of Zoloft (sertraline) (higher than 200 mg). Some people need additional medications to augment the Zoloft (sertraline). Hope you have a good response. Take care.
Answered 4/13/2015
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