A 18-year-old male asked:
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is there a difference between histamine and methacholine?

1 doctor answer
Dr. David Bare
49 years experience Family Medicine
Yes different: Histamine a compound that is released by cells in response to injury and in allergic and inflammatory reactions, causing contraction of smooth muscle and dilation of capillaries. Methacholine is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system. both are use to test for airway reactivity in asthma.
Answered on Jun 9, 2015
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Related questions:

A 18-year-old male asked:
Dr. John Chiu
Dr. John Chiu answered
56 years experience Allergy and Immunology
It may potentially: Antihistamines are not to be taken for at least 24 hrs but preferably 72 hrs prior a methacholine challenge. Having said that , I would doubt the aver ... Read More
A 18-year-old male asked:
Dr. Al Hegab
Dr. Al Hegab answered
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None: but why do you want to evade the test?
A 65-year-old male asked:
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Different: PFT measures your lung function in its current state. Methacholine challenge is often used when the lung function test is normal but asthma is suspect ... Read More
A 34-year-old member asked:
Dr. Robert Ramirez
17 years experience Allergy and Immunology
It's hard: An experienced physician, pulmonologist, allergist, etc. Is able to tell when patients are not putting enough effort into a test.
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