How do you diagnose hemoglobin e-beta thalassemia?

Pediatric Hematolo-: gists have the expertise to diagnose & treat Hb E/β-thalassaemia, which results from co-inheritance of a β-thalassaemia allele, an alternative form of a gene, from 1 parent and the structural variant Hemoglobin E from the other. They check for co-inheritance of α-thalassemia & polymorphisms, 2 or more alleles at 1 locus, that ^ synthesis of Fetal Hb. These are factors that determine severity.