Can i.take oxcycodone,trazadone and tylenol3 together?

#3, Traz & Oxycodone: Hello. No reason to be taking both #3 and oxycodone together. Stick to one agent. Keep the use to the bare minimum because of the known short AND long term side effects. Trazadone is normally sedating and thus taken at night. For some patients, #3 or oxycodone taken at same time as trazadone can cause increased sedation and other side effects. Talk to your prescriber about staggered doses of meds.