A member asked:

All other blood work is normal. can you still have polymyositis even with normal blood work?

5 doctors weighed in across 2 answers

Very rarely: That is extremely rare but polymyositis can occur with normal muscle enzymes. However, the clinical picture must fit and the EMG and muscle biopsy should confirm the diagnosis.

Answered 3/19/2015

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I'd be surprised: I've devoted my life to lab medicine. Only if the history and physical exam are almost screaming "Polymyositis!" would I consider proceeding with muscle biopsy / EMG.

Answered 5/2/2015

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