My wife is diabatic patient and insuline dependent.now with passage of time she underwent severe depression attack and with indesgation proalem.advise?

Behavioral Health: It may be very beneficial for her to see a psychiatrist &/or a psychologist to help her through her depression.

She needs treatment: There are many effective treatments available for depression and i would encourage her to consult your/her doc as soon as feasible. I think that by knowing/recognizing that she is having a problem is a huge step toward improvement! it is not easy to get motivated when you are down. Depression needs to be treated or else her medical problems will worsen. Don't delay. Consult doc. Good luck.